1. Oxymetazoline (Afrin)
Oxymetazoline is a drug used in a widely-used commercial nasal spray called Afrin. It does not have a particularly strong high, and is instead more likely to cause psychosis in those who use it, some of whom have reported recurring hallucinations. What makes this drug noteworthy is just how addicting it is. Doctors have found that those hooked on it simply cannot function without the drug. The packaging for Afrin tells you not to use the drug for more than a few days at a time; the reason for this is that, if used for too long, it actually causes the inner part of the nose to swell up. In essence, using it too much defeats the purpose of decongesting your nose, and makes you constantly reliant on more nasal spray, so that you can breathe. Don’t pick up this habit, unless you want nasal inhalers scattered all over your home, car, and workspace.